Production of monoclonal antibodies against bacterial adhesins

Details Production of monoclonal antibodies against bacterial adhesins Production of monoclonal antibodies against bacterial adhesins

C - Chemistry, Metallurgy

12

N

167/139, 167/37,

C12N 15/00 (2006.01) C07K 14/245 (2006.01) C07K 16/12 (2006.01) C12N 5/02 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1187822

ABSTRACT OF THE DISCLOSURE Monoclonal antibodies specific for surface antigens of bacteria which act as adhesins between prokaryotic and eukaryotic cells and, in particular, K-99 pili, and methods for production thereof are described. These monoclonal antibodies may be used for the prophylactic and therapeutic treatment of diseases induced by adhesin-bearing pathogens in animals and humans, and for the diagnostic identification of adhesin-bearing bacteria.

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