Production of peptides in plants as viral coat protein fusions

Details Production of peptides in plants as viral coat protein fusions Production of peptides in plants as viral coat protein fusions

C - Chemistry, Metallurgy

12

N

C12N 7/00 (2006.01) A01N 1/00 (2006.01) A61K 39/12 (2006.01) A61K 48/00 (2006.01) A61P 31/12 (2006.01) C07K 16/08 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2497798

Vaccines and diagnostic composition are made and used for preventing, treating and detecting antigens from a papilloma virus, ebola virus, HIV virus, Rift Valley Fever virus or a parvovirus. The epitopes of these viruses are produced as genetically engineered fusion peptides in plants by infection with a recombinant tobamovirus vectors to express fusion proteins containing the epitope peptides.

L'invention concerne des vaccins et une composition de diagnostic fabriqués et utilisés en vue de prévenir, traiter et détecter des antigènes provenant du papillomavirus, du virus d'Ebola, du VIH, du virus de la fièvre de la vallée du Rift ou du parvovirus. Les épitopes de ces virus sont produits comme des peptides de fusion génétiquement modifiés dans des plantes par infection au moyen de vecteurs recombinants du tobamovirus en vue d'exprimer des protéines de fusion contenant les peptides de l'épitope.

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