Production of polyelectrolyte capsules by surface precipitation

B - Operations – Transporting – 01 – J

Patent

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B01J 13/02 (2006.01) A61K 9/50 (2006.01) B01J 13/10 (2006.01) B01J 13/22 (2006.01)

Patent

CA 2417792

The invention concerns a method for producing nanocapsules and microcapsules comprising a polyelectrolyte shell by surface precipitation from the solution, by applying a shell to template particles comprising the steps (a) providing a dispersion of template particles of suitable size in a salt-containing liquid phase which contains the components required to form the shell in a dissolved form and (b) precipitating the components from the liquid phase onto the template particles under conditions which enable the formation of a shell around the template particles that has a thickness of from 1 to 100 nm.

L'invention concerne un procédé pour produire des nanocapsules ou des microcapsules, comprenant une enveloppe de polyélectrolyte, par précipitation superficielle à partir d'une solution et par application d'une enveloppe sur les particules de matrice. Ce procédé comprend les étapes suivantes : (a) mise à disposition d'une dispersion de particules de matrice de dimensions appropriées dans une phase liquide saline contenant les composants nécessaires à la formation de l'enveloppe, sous forme dissoute ; et (b) précipitation des composants à partir de la phase liquide sur les particules de matrice dans des conditions permettant la formation d'une enveloppe, présentant une épaisseur comprise entre 1 et 100 nm, autour des particules de matrice.

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