C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) C12N 9/00 (2006.01) C12N 9/10 (2006.01) C12N 9/12 (2006.01) C12N 15/31 (2006.01) C12N 15/52 (2006.01) C12N 15/70 (2006.01) C12N 15/81 (2006.01) C12N 15/90 (2006.01) C12P 7/42 (2006.01) C12P 19/62 (2006.01)
Patent
CA 2274087
Hybrid and novel polyketide synthases and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction of improved libraries of PKS and polyketides. In addition, polyketides can be produced in hosts that ordinarily do not produce polyketides by supplying, along with an expression system for the desired PKS, an expression system for holo ACP synthase.
L'invention porte sur de nouvelles synthases de polycétides (PKS) hybrides et de nouveaux polycétides hybrides produits à l'aide d'un système de vecteurs multiples. Les possibilités combinatoires offertes lorsqu'on place les différentes activités catalytiques des systèmes de PKS sur des vecteurs séparés permettent la constitution de bibliothèques améliorées de PKS et de polycétides. De plus, les polycétides peuvent être produits dans des hôtes ne produisant pas ordinairement de polycétides, en utilisant parallèlement au système d'expression des PKS désirés un système d'expression de l'holosynthase PTA.
Ashley Gary W.
Barr Philip J.
Santi Daniel V.
Ziermann Rainer
Fetherstonhaugh & Co.
Kosan Biosciences Inc.
LandOfFree
Production of polyketides in bacteria and yeast does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of polyketides in bacteria and yeast, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of polyketides in bacteria and yeast will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1781011