Production of polypeptides by improved secretion

Details Production of polypeptides by improved secretion Production of polypeptides by improved secretion

C - Chemistry, Metallurgy

07

K

C07K 14/14 (2006.01)

Patent

CA 2568788

The present invention relates to polypeptides that have an activity corresponding to at least one activity of the SEC61 polypeptide, polynucleotides encoding these polypeptides and the use thereof in the preparation of host cells suitable for production of a polypeptide of interest. Such host cells may have an increased capacity to secrete a polypeptide of interest.

L'invention concerne des polypeptides qui possèdent une activité correspondant à au moins une activité du polypeptide SEC61, des polynucléotides codant ces polypeptides ainsi que leur utilisation dans la préparation de cellules hôtes convenant à la production du polypeptide recherché. Ces cellules hôtes peuvent présenter une capacité sécrétoire accrue du polypeptide recherché.

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