Production of polysialic acid containing glyconjugates using...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/54 (2006.01) C12N 9/10 (2006.01) C12N 15/63 (2006.01) C12P 19/00 (2006.01) C12P 19/26 (2006.01)

Patent

CA 2638779

The invention relates to a fusion protein comprising a bifunctional sialytransferase and a poly-sialytransferase and methods to use the fusion proteins for production of poly-sialylated end products, e.g. oligosaccharides and glycoproteins.

L'invention concerne une protéine de fusion comprenant une sialyltransférase et une poly-sialyltransférase bifonctionnelles, ainsi que des méthodes d'utilisation de ces protéines de fusion afin de préparer des produits finis poly-sialylés, par exemple, des oligosaccharides et des glycoprotéines.

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