Production of pyrrolidin-2-ones from 2-pyrrolin-2- ones and...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/26 (2006.01) C07D 207/267 (2006.01) C07D 207/27 (2006.01) C07D 207/38 (2006.01) C07F 9/54 (2006.01)

Patent

CA 1108628

PRODUCTION OF PYRROLIDIN-2-ONES FROM 3-PYRROLIN-2-ONES AND THE PRODUCTION OF 3-PYRROLIN-2-ONES ABSTRACT OF THE DISCLOSURE Pyrrolidin-2-ones are produced by hydrogenation of 3-pyrrolin-2-ones, which latter compounds could not prior to this invention be easily obtained. These 3-pyrrolin-2-ones with various substituents are produced by ring closure of N-aroylmethyl-acetamides. The ring closure is effected in basic media under nitrogen.

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