C - Chemistry – Metallurgy – 12 – M
Patent
C - Chemistry, Metallurgy
12
M
C12M 1/12 (2006.01) C12M 1/00 (2006.01) C12N 15/09 (2006.01) C12P 1/00 (2006.01) C12P 1/02 (2006.01) C12P 19/34 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2613238
The invention provides for a method of producing at least one recombinant product under aerated conditions. The method includes providing a porous substrate having a first side and a second side and which has a biofilm of microorganisms attached to the first side thereof, the substrate being configured to allow passage of a nutrient solution therethrough and to prevent the passage of microorganism cells therethrough. The method further includes causing a nutrient solution to flow through the substrate and the biofilm in a direction from the second side thereof to the first side thereof under aerated conditions, at a rate which is sufficiently low for a nutrient gradient having a concentration differential to be established across the biofilm, and the microorganisms being induced to produce recombinant product.
L'invention concerne un procédé permettant de produire au moins un produit recombiné dans des conditions aérées. Ce procédé consiste à prendre un substrat poreux qui présente un premier et un second côté, et qui comprend un film biologique de micro-organismes fixé sur le premier côté, ce substrat étant conçu pour permettre le passage d'une solution nutritive et pour empêcher le passage de cellules de micro-organismes. Ce procédé consiste à faire en outre circuler une solution nutritive à travers le substrat et le film biologique, du premier côté en direction du second côté, dans des conditions aérées, à une vitesse suffisamment lente pour permettre l'établissement d'un gradient de nutriments présentant un différentiel de concentration à travers le film biologique, et pour amener les micro-organismes à produire un produit recombiné.
Fraser Sheena Janet
Leukes Winston Daniel
Blake Cassels & Graydon Llp
Synexa Life Sciences (proprietary) Limited
LandOfFree
Production of recombinant products using capillary membranes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Production of recombinant products using capillary membranes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Production of recombinant products using capillary membranes will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1456838