Production of reprogrammed pluripotent cells

Details Production of reprogrammed pluripotent cells Production of reprogrammed pluripotent cells

C - Chemistry, Metallurgy

12

N

C12N 5/077 (2010.01) C12N 15/06 (2006.01) C12N 15/07 (2006.01)

Patent

CA 2755870

The present invention provides a method of producing a reprogrammed cell, said method comprising exposing Stro-1+ multipotential cells and/or progeny cells thereof to one or more potency-determining factors under conditions sufficient to reprogram the cells. The present invention also provides cells produced by such a method and cells differentiated therefrom in ad-dition to various uses of those cells.

La présente invention a pour objet un procédé de production d'une cellule reprogrammée, ledit procédé comprenant l'exposition de cellules pluripotentes Stro-1+ et/ou de leurs cellules filles à un ou plusieurs facteurs de détermination de l'activité dans des conditions suffisantes pour reprogrammer les cellules. La présente invention concerne également les cellules produites par un tel procédé et les cellules différenciées à partir de celles-ci, en plus de diverses utilisations de ces cellules.

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