Production of serum albumin

Details Production of serum albumin Production of serum albumin

A - Human Necessities

61

K

530/15.06

A61K 35/16 (2006.01) C07K 14/765 (2006.01)

Patent

CA 1069820

Abstract of the Disclosure A serum albumin fraction is prepared in high yield and purity from plasma and other albumin-containing blood protein fractions by contacting with a resinous polymeric material having a high capacity for adsorption of albumin, heating at 65°C - 72°C for about 1-4 hours while maintaining a pH of 5.0 - 5.5, and then selectively eluting the albumin from the resin-protein mixture at a pH of 3.5 - 4.5. The resinous polymeric materials are water-insoluble, cross-linked polyelectrolyte copolymers of ethylene and maleic anhydride containing pendant dimethylaminopropyl functional groups. - 1 -

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