Production of specific immune nucleic acids cell dialysates...

C - Chemistry – Metallurgy – 12 – P

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167/139, 195/1.1

C12P 19/30 (2006.01) A61K 35/14 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 16/00 (2006.01)

Patent

CA 1110988

A B S T R A C T Gamma-globulins and immune nucleic acids, both specific to a given antigen, are produced by culturing in vitro an inducible cell line in the presence of specific immune nucleic acids or specific immune dialysates obtained either from human or animal donor lymphoid cells sensitized to said specific antigen or from cells of a previously induced cell line sensitized to said specific antigen, or in the presence of the liquid phase of a culture of a previously induced cell line sensitized to said specific antigen; and extracting gamma-globulins from the liquid phase of the thus induced cell culture and/or extracting the immune nucleic acids from the cells so cultured. Specific immune dialysates may also be produced by a similar process.

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