Production of thermolysin and variants thereof, and use in...

Details Production of thermolysin and variants thereof, and use in... Production of thermolysin and variants thereof, and use in...

C - Chemistry, Metallurgy

12

N

C12N 9/54 (2006.01)

Patent

CA 2704311

The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or catalytic activity. In some embodiments, the thermolysin finds use in cleaning and other applications comprising detergent. In some particularly preferred embodiments, the present invention provides methods and compositions comprising thermolysin formulated and/or engineered to resist detergent-induced inactivation.

La présente invention concerne des procédés et des compositions comprenant au moins une enzyme protéase neutre analogue à la thermolysine dont la stabilité en stockage et/ou l'activité catalytique sont améliorées. Dans certains modes de réalisation, la thermolysine trouve une utilisation dans le domaine du nettoyage et dans d'autres applications comprenant un détergent. Dans certains modes de réalisation particulièrement préférés, la présente invention concerne des procédés et des compositions comprenant de la thermolysine formulée et/ou conçue pour résister à une inactivation induite par un détergent.

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