A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/19 (2006.01)
Patent
CA 2599861
A process for producing a pharmaceutical lozenge formulation comprising the steps of: (a) providing a liquid composition comprising a salt of a non- steroidal anti-inflammatory drug (NSAID salt) and a solvent system, (b) providing a molten lozenge-forming composition, (c) mixing the liquid composition with the molten lozenge-forming composition, and, (d) forming the resulting mixture into lozenges each containing a therapeutically effective amount of said NSAID salt/NSAID mixture. The present application discloses the corresponding NSAID-containing lozenge compositions and their use for the manufacture of a medicament for treating sore throat.
L~invention concerne un procédé de fabrication d~une formulation de losange pharmaceutique comprenant les phases suivantes : (a) fourniture d~une composition liquide comprenant un sel de médicament anti-inflammatoire non stéroïde (sel de type NSAID) et un système solvant, (b) fourniture d~une composition de formation de losange en fusion, (c) mélange de la composition liquide avec la composition de formation de losange en fusion, et, (d) formation du mélange résultant en losanges, contenant chacun une quantité efficace thérapeutique dudit sel NSAID/mélange NSAID. La présente demande divulgue les compositions en losanges contenant le NSAID correspondantes et leur utilisation pour la fabrication d~un médicament pour traiter le mal de gorge.
Fanfarillo Michael
Marshall Paul
Sawicka Kirsty
Takhar Jasmine
Mccarthy Tetrault Llp
Reckitt Benckiser Healthcare (uk) Limited
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