Production scale method of forming microparticles

Details Production scale method of forming microparticles Production scale method of forming microparticles

A - Human Necessities

61

K

A61K 9/16 (2006.01) B01J 13/02 (2006.01)

Patent

CA 2221496

The present invention relates to a method for forming microparticles of a material from microdroplets of a solution, wherein the solution comprises the material dissolved in a solvent. The method includes the steps of directing the microdroplets into a freezing zone, wherein the freez-ing zone is surrounded by a liquified gas, and wherein the microdroplets freeze. The frozen microdroplets are then mixed with a liquid non-solvent, whereby the solvent is ex-tracted into the non-solvent, thereby forming the micropar-ticles.

Cette invention porte sur un procédé d'élaboration de microparticules d'un matériau à partir de microgouttelettes d'une solution, la solution comportant ledit matériau dissout dans un solvant. Ce procédé consiste à diriger les microgouttelettes vers une zone de congélation entourée de gaz liquéfié dans laquelle elles se congèlent. On mélange ces microgouttelettes une fois congelées à un non-solvant liquide, le solvant étant alors extrait des microgouttelettes et dirigé vers le non-solvant, ce qui entraîne la formation des microparticules.

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