Progestin-containing drug delivery system

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 9/70 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2732211

The present invention relates to drug delivery compositions in the form of thin water-soluble films (wafers), which contain small particles that comprise at least one progestin and at least one protective agent. The protective agent provides effec-tive taste-masking of the progestin due to limited release of the progestin in the mouth. The progestin is hence not absorbed via the buccal route, but rather via the enteral (per-oral) route.

La présente invention concerne des compositions d'administration de médicament sous la forme de films minces solubles dans l'eau (cachets), qui contiennent de petites particules qui comportent au moins un progestatif et au moins un agent protecteur. L'agent protecteur fournit un masquage efficace du goût du progestatif en raison d'une libération limitée du progestatif dans la bouche. Le progestatif est par conséquent non absorbée par voie buccale, mais plutôt par voie entérale (per orale).

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