Prognosis prediction for colorectal cancer

G - Physics – 01 – N

Patent

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Details

G01N 33/50 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2640352

This invention relates to prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for colorectal cancer. Specifically, this invention relates to the use of genetic markers for the prediction of the prognosis of cancer, such as colorectal cancer, based on signatures of genetic markers. In various aspects, the invention relates to a method of predicting the likelihood of long-term survival of a cancer patient, a method of determining a treatment regime for a cancer patient, a method of preparing a treatment modality for a cancer patient, among other methods as well as kits and devices for carrying out these methods.

La présente invention concerne des signatures pronostiques, ainsi que des compositions et des procédés permettant de déterminer l~évolution d~un cancer chez un patient, en particulier un cancer colorectal. L~invention concerne spécifiquement l~utilisation de marqueurs génétiques permettant de prédire l~évolution d~un cancer, notamment un cancer colorectal, en se basant sur les signatures des marqueurs génétiques. Sous plusieurs de ses aspects, cette invention concerne : un procédé de prédiction de la probabilité de survie à long terme d~un patient atteint d~un cancer ; un procédé permettant de déterminer un régime de traitement d~un patient atteint d~un cancer ; et un procédé permettant d~élaborer une modalité de traitement d~un patient atteint d~un cancer, entre autres procédés ; l~invention concerne également des kits et des dispositifs pour mettre en AEuvre lesdits procédés.

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