Prognostic and predictive gene signature for non-small cell...

C - Chemistry – Metallurgy – 40 – B

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C40B 40/06 (2006.01) C12Q 1/68 (2006.01) C40B 30/02 (2006.01) C40B 30/04 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) G06F 19/00 (2011.01)

Patent

CA 2761571

The application provides methods of prognosing and classifying lung cancer patients into poor survival groups or good survival groups and for determining the benefit of adjuvant chemotherapy by way of a multigene signature. The application also includes kits and computer products for use in the methods of the application.

Linvention concerne des procédés permettant détablir un pronostic et de réaliser une classification des patients atteints dun cancer du poumon, dans des groupes à faible pronostic de survie ou dans des groupes à bon pronostic de survie, et permettant de déterminer le bénéfice dune chimiothérapie adjuvante au moyen dune signature multigénique. Linvention concerne également des kits et des produits informatiques utilisés dans le cadre des procédés de la demande de brevet.

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