Prognostic method

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/04 (2006.01) G06F 19/18 (2011.01) C07H 21/00 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01) C40B 30/00 (2006.01) C40B 30/04 (2006.01) C40B 40/06 (2006.01)

Patent

CA 2657616

A method for prognosing recurrence of prostate cancer (PCa) in a subject following prostatectomy using the outcomes of selected single nucleotide polymorphisms (SNPs) and clinical variables. A method for genotyping PCa associated genetic variations comprising use of a DNA micorarray. A microarray for use in the described methods.

L'invention concerne une méthode qui permet de pronostiquer la récurrence du cancer de la prostate (PCa) chez un sujet, à la suite d'une prostatectomie, au moyen des résultats de polymorphismes mononucléotidiques choisis (SNP) et de variables cliniques. Elle concerne également une méthode de génotypage de variations génétiques associées au PCa consistant à utiliser un jeu ordonné de microéchantillons d'ADN. Elle concerne en outre un jeu ordonné de microéchantillons utilisable avec les méthodes de l'invention.

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