C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/07 (2010.01) A61L 27/38 (2006.01) C12N 5/00 (2006.01) C12Q 1/02 (2006.01) C40B 50/00 (2006.01) G01N 33/50 (2006.01) A61K 35/12 (2006.01)
Patent
CA 2500410
The present invention relates to a programmable scaffold, which is a three- dimensional scaffold having interconnected pores and biologically active molecules physically entrapped therein. The scaffold is a lyophilized hydrogel of a polymer. The scaffold can be used in an array on a platform and loaded with various combinations of biologically active molecules for high throughput and parallel screening, as well as tissue engineering. The present invention also relates to methods for making and modifying the scaffolds.
L'invention concerne un échafaudage programmable, soit un échafaudage tridimensionnel possédant des pores interconnectés dans lesquels des molécules biologiquement actives sont physiquement piégées. L'échafaudage est un hydrogel lyophilisé d'un polymère. On peut utiliser l'échafaudage dans un réseau sur une plate-forme chargée de diverses combinaisons de molécules biologiquement actives aux fins d'un rendement et d'un criblage parallèle élevés ainsi que dans le domaine du génie tissulaire. L'invention concerne également des procédés de fabrication et de modification de ces échafaudages.
Heidaran Mohammad
Rowley Jonathan
Becton Dickinson And Company
Gowling Lafleur Henderson Llp
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