Programmed release tablets containing naproxen

Details Programmed release tablets containing naproxen Programmed release tablets containing naproxen

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 9/20 (2006.01) A61K 9/22 (2006.01)

Patent

CA 2105541

Programmed release tablets, to be administered by oral route, containing from 500 to 1,200 mg of naproxen, made by mixtures of an immediate release granulate dry compact containing from 5% to 28% of naproxen, of a controlled release granulate dry compact containing from 72% to 95% of naproxen and of a disintegrating agent. A portion of naproxen is released in a short time, so that the drug can quickly develop its therapeutic action reaching the necessary hematic levels, while the remaining portion is released in a longer interval of time, so as to allow the therapeutic coverage till the subsequent administration. The therapeutic coverage is effective for a period of 24 hours; thus the tablets object of the present invention are suitable for a once a day administration.

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