C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/575 (2006.01) A61K 38/22 (2006.01) A61P 5/00 (2006.01) A61P 25/04 (2006.01) C07K 14/72 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2380573
The present invention relates to a method for regulating autonomic functions, such as blood pressure, and further to a method for treating pain by prolactin-releasing peptide (PrRP) or through its receptor. This peptide regulates blood pressure and pain mechanisms, and is expressed in complementary areas with neuropeptide FF (NPFF). Specific antisera developed against the N- and/or C-terminal domains of PrRP may be used for diagnostics.
La présente invention concerne une méthode destinée à la régulation de fonctions autonomes, telles que la pression artérielle, ainsi qu'une méthode de traitement de la douleur au moyen d'un peptide libérant de la prolactine (PrRP) ou de son récepteur. Ce peptide régule la pression artérielle et les mécanismes liés à la douleur. Il est exprimé dans des zones complémentaires avec un neuropeptide FF (NPFF). On peut utiliser des antisérums développés contre les domaines N-terminal et/ou C-terminal de PrRP pour effectuer des diagnostics.
Kalso Eija
Korpi Esa
Panula Pertti Aarre Juhani
Pertovaara Antti
Oy Juvantia Pharma Ltd.
Oyen Wiggs Green & Mutala Llp
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