A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/195 (2006.01) C07C 225/06 (2006.01) C07C 229/34 (2006.01) C07C 233/22 (2006.01) C07C 235/34 (2006.01) C07C 271/16 (2006.01) C07C 271/18 (2006.01) C07C 275/24 (2006.01) C07C 275/28 (2006.01) C07C 275/30 (2006.01) C07C 275/34 (2006.01) C07C 317/28 (2006.01) C07C 317/36 (2006.01) C07C 317/44 (2006.01) C07C 323/52 (2006.01) C07F 9/50 (2006.01)
Patent
CA 2438492
PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipo-protein-cholesterol and to lower certain plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases, in mammals, including humans.
L'invention concerne des activateurs alpha de PPAR, des compositions pharmaceutiques contenant de tels composés, ainsi que l'utilisation de tels composés pour élever certains taux de lipides plasmatiques, notamment le cholestérol à lipoprotéines de haute densité (HDL), et pour abaisser d'autres taux de lipides plasmatiques tels que le cholestérol à lipoprotéines de faible densité (LDL) et les triglycérides, et de ce fait pour traiter des maladies exacerbées par de faibles taux de cholestérol HDL et/ou des taux élevés de cholestérol LDL et de triglycérides, telles que l'athérosclérose et des maladies cardiovasculaires, chez les mammifères, y compris chez les humains.
Hayward Cheryl Myers
Perry David Austen
Pfizer Products Inc.
Smart & Biggar
LandOfFree
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