Prolonged-action multiple-layer tablets

Details Prolonged-action multiple-layer tablets Prolonged-action multiple-layer tablets

A - Human Necessities

61

K

167/171

A61K 9/24 (2006.01) A61K 9/42 (2006.01)

Patent

CA 1199870

PROLONGED-ACTION MULTIPLE-LAYER TABLETS Abstract of the Disclosure: A prolonged-action multiple-layer tablet having an increased rate of dissolution of the active ingredient from a given point of time onward is disclosed. The tablet comprises layer A made of an intimate mixture of a water-insoluble wax that has an average particle size of 10 µm or less and which is solid at ordinary temperatures, a disintegrator and a binder, and layer B made of an intimate mixture of a water- insoluble wax that has an average particle size of 10 µm or less and which is solid at ordinary temperatures, a dis- integrator, a binder and the active ingredient. In the tablet, a quick-release layer containing the active ingredient may be formed on either layer A or B.

410769

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