Prolonged release formulation of active principles having a...

Details Prolonged release formulation of active principles having a... Prolonged release formulation of active principles having a...

A - Human Necessities

61

K

A61K 9/24 (2006.01) A61K 9/36 (2006.01) A61K 31/437 (2006.01) A61K 47/12 (2006.01)

Patent

CA 2611125

The invention concerns a novel formulation for prolonged release of an active principle having a pH-dependent solubility. The inventive formulation comprises a matrix support based on hydrophilic polymer containing a specific dose of active principle, and further comprises on or more acidifying agents in the form of an acid salt of an organic acid.

L'invention concerne une nouvelle formulation pour une libération prolongée d'un principe actif présentant une solubilité dépendante du pH. La formulation de l'invention comprend un excipient matriciel à base de polymère hydrophile renfermant une dose déterminée de principe actif, et comprend également un ou plusieurs agents acidifiants sous forme d'un sel acide d'un acide organique.

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