Prolonged release therapeutic composition based on...

A - Human Necessities – 61 – K

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A61K 9/22 (2006.01) A61K 9/20 (2006.01) A61K 47/00 (2006.01)

Patent

CA 1195929

PROLONGED RELEASE THERAPEUTIC COMPOSITIONS BASED ON HYDROXYPROPYLMETHYLCELLULOSE ABSTRACT A carrier base material combined with a therapeutically active medicament and shaped and compressed to a solid unit dosage form having a regular and prolonged release pattern upon administration, the carrier base material being hydroxypropylmethylcellulose or a mixture of hydroxypropylmethlylcellulose and up to 30% by weight of the mixture of ethylcellulose and/or up to 30% by weight of the mixture of sodium carboxymethylcellulose, and wherein the hydroxy- propylmethylcellulose has a hydroxypropoxyl content of 9-12 weight-% and a number average molecular weight of less than 50,000.

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