Prolyl hydroxylase inhibitors

Details Prolyl hydroxylase inhibitors Prolyl hydroxylase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 239/54 (2006.01) A61K 31/505 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2655491

The invention described herein relates to certain pyrimidinetrione N-substituted glycine derivatives of formula (I), which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.

La présente invention concerne certains dérivés de glycine N-substitués de type pyrimidinetrione de formule (I) qui sont des antagonistes de HIF prolyle hydroxylases et qui peuvent être employés dans le traitement de maladies bénéficiant de l'inhibition de cette enzyme, par exemple l'anémie.

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