Promoter for the expression of foreign genes in neuronal cells

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/09 (2006.01) A01K 67/027 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2604241

The invention relates to a promoter comprising a Thy-1 mammal-derived nucleic acid sequence, which brings about the neuronal-specific transcription of a heterologous nucleic acid sequence sensitive from 3' downwards to the promoter in mammalian and non-mammalian cells.

Promoteur comprenant une séquence d'acide nucléique dérivée de Thy-1 de mammifères, qui provoque la transcription spécifique des neurones d'une séquence d'acide nucléique hétérologue se trouvant en position 3' en aval par rapport au promoteur, aussi bien dans des cellules de mammifères que dans des cellules de non-mammifères.

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