Promoters exhibiting endothelial cell specificity and...

Details Promoters exhibiting endothelial cell specificity and... Promoters exhibiting endothelial cell specificity and...

C - Chemistry, Metallurgy

12

N

C12N 15/79 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) A61P 9/10 (2006.01) C07K 14/575 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12N 15/85 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2429342

An isolated polynucleotide functional as a promoter in eukaryotic cells is disclosed. The isolated polynucleotide includes an endothelial specific enhancer element as detailed herein. Further disclosed is a method of expressing a nucleic acid sequece of interest in endothelial cells.

L'invention concerne un polynucléotide isolé exerçant une fonction de promoteur dans des cellules eucaryotes. Ce polynucléotide isolé comprend un élément amplificateur spécifique pour des cellules endothéliales. Elle concerne également un procédé d'expression d'une séquence d'acides nucléiques dans des cellules endothéliales.

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