Promoters of filamentous fungi and use thereof

Details Promoters of filamentous fungi and use thereof Promoters of filamentous fungi and use thereof

C - Chemistry, Metallurgy

12

N

195/1.2, 195/1.2

C12N 15/80 (2006.01) C12N 1/15 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1341608

Novel vectors are disclosed for use in filamentous fungi such as Aspergillus sp. in particular, whereby protein coding regions may be inserted therein to achieve expression or expression followed by secretion of the coded protein from the host. Signal peptide sequences and promoter sequences valuable for this purpose are disclosed as are expression vectors containing coding regions native or foreign to the fungal host. In accordance with the invention, a filamentous fungus such as Aspergillus may be provided with foreign or natural coding regions associated with foreign or natural promoter sequences and optionally signal peptide sequences which can be used to control the expression and/or secretion of the proteins encoded by these coding regions.

617097

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