C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/64 (2006.01) A61K 31/4412 (2006.01) A61K 31/443 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2373180
A method for the inhibition of the binding of .alpha.4.beta.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which .alpha.4.beta.1 is involved.
La présente invention concerne un procédé permettant d'inhiber la liaison de l'intégrine alpha 4 beta 1 à ses récepteurs, par exemple à la molécule d'adhésion cellulaire vasculaire 1 et la fibronectine. L'invention a aussi pour objet des composés qui inhibent cette liaison, des compositions pharmaceutiquement actives comprenant ces composés, et l'utilisation de ces derniers tels quels ou dans des formulations pour contrôler ou prévenir des maladies dans lesquelles l' alpha 4 beta 1 joue un rôle important.
Biediger Ronald J.
Holland George W.
Kassir Jamal M.
Li Wen
Market Robert V.
Encysive Pharmaceuticals Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Texas Biotechnology Corporation
LandOfFree
Propanoic acid derivatives that inhibit the binding of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Propanoic acid derivatives that inhibit the binding of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Propanoic acid derivatives that inhibit the binding of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1454806