C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/86 (2006.01) A61K 31/435 (2006.01)
Patent
CA 2361285
A method for the inhibition of the binding of .alpha.4.beta.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which .alpha.4.beta.1 is involved.
Biediger Ronald J.
Dupre Brian
Hamaker Linda K.
Holland George W.
Kassir Jamal M.
Encysive Pharmaceuticals Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Texas Biotechnology Corporation
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