Propargyl phenyl ether a2a receptor agonists

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 19/16 (2006.01) A61K 31/7076 (2006.01) A61K 49/00 (2006.01) A61P 7/02 (2006.01) A61P 9/08 (2006.01) A61P 29/00 (2006.01) C07D 473/00 (2006.01)

Patent

CA 2375385

2-adenosine propargyl phenyl ether compounds having formula (A) and methods for using the compounds as A2A receptor agonists to stimulate mammalian coronary vasodilatation for therapeutic purposes and for purposes of imaging the heart.

Composés de 2-adénosine propargyl phényl éther représentés par la formule (A) et procédés d'utilisation de ces composés en tant qu'agonistes du récepteur A2A afin de stimuler la vasodilatation coronaire mammifère à des fins thérapeutiques et dans le but de prendre une image du coeur.

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