C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/08 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) C07H 21/00 (2006.01) C07K 1/34 (2006.01) C07K 7/06 (2006.01) C07K 16/18 (2006.01)
Patent
CA 2522703
A new class of lipopeptides has been surprisingly discovered from mammalian serum that are potent immunoregulators, hereinafter, referred to as Immune Cell Potentiating Factors ("ICPF"s). The clinical and laboratory data show a wide range of prophylactic and therapeutic applications for the ICPFs including primary and adjunctive therapy in the treatment of diseases of both bacterial and viral origin as well as certain neoplastic diseases. Described herein are chemical structures of ICPF of the invention, the likely mode of action, and the surprisingly broad spectrum of therapeutic efficacy and wide margin of safety to the host species.
L'invention concerne une classe de lipopeptides issus d'un sérum mammifère qui sont de puissants immunorégulateurs, appelés ici, facteurs de potentialisation de cellules immunes ("ICPF"). Les données cliniques et de laboratoire présentent une large gamme d'applications prophylactiques et thérapeutiques pour les ICPF, notamment une thérapie primaire et complémentaire dans le traitement de maladies d'origine aussi bactérienne que virale, ainsi que de maladies néoplasiques. L'invention concerne également des structures chimiques des ICPF selon l'invention, le mode probable d'action, le spectre étonnamment large d'efficacité thérapeutique et la grande marge de sécurité conférée aux espèces hôtes.
Fuhrer J. Peter
Thacker James D.
Willeford Kenneth O.
Argyll Biotechnologies Llc
Genebact Biotechnologies Inc.
Ledgley Law
Mississippi State University
LandOfFree
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