Prophylactic and therapeutic use of hydroxysteroids

Details Prophylactic and therapeutic use of hydroxysteroids Prophylactic and therapeutic use of hydroxysteroids

A - Human Necessities

61

K

A61K 31/56 (2006.01) A61P 9/10 (2006.01) A61P 13/12 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2457050

3-Hydroxy-7-hydroxy steroids and 3-oxo-7-hydroxy steroids, especially the 7.szlig.-isomers thereof, and pharmaceutically acceptable esters thereof are useful for protection against ischaemia-induced damage to peripheral organs, such as the heart or kidneys, as well as treatment of spiral cord injury.

L'invention concerne des 3-hydroxy-7-hydroxy stéroïdes et des 3-oxo-7-hydroxy stéroïdes, plus particulièrement leurs 7.szlig.-isomères, et leurs esters pharmaceutiquement acceptables utilisés dans la protection contre les lésions induites par l'ischémie affectant les organes périphériques, notamment le coeur ou les reins, ainsi que le traitement des blessures médullaires.

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