Prophylactic drug for prevention of alcoholic gastritis

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) A61K 31/425 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01)

Patent

CA 2320421

Preventives for acute alcoholic gastritis containing a combination of sucralfate with histamine H2 receptor antagonists, preferably famotidine. Compared with the case where each active ingredient is used alone, the above drugs show remarkable synergistic effects of preventing acute alcoholic gastritis. The combined use of these two ingredients makes it possible to considerably reduce the administration dose.

L'invention porte sur des médicaments préventifs des gastrites alcooliques comportant une combinaison de sucralfate et d'agonistes du récepteur H¿2? de l'histamine, de préférence de la famotidine. Par comparaison à l'emploi séparé des deux principes actifs, la combinaison des deux médicaments a des effets synergiques remarquables en matière de prévention des gastrites alcooliques, ce qui permet de réduire considérablement les doses administrées.

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