Prophylactic or therapeutic agent for eye disease...

Details Prophylactic or therapeutic agent for eye disease... Prophylactic or therapeutic agent for eye disease...

A - Human Necessities

61

K

A61K 31/41 (2006.01) A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61K 9/20 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01) C07D 293/06 (2006.01)

Patent

CA 2716466

The present invention provides a novel pharmaceutical use of 2-phenyl-l,2-benzisoselenazol-3(2H)- one or a salt thereof. 2-Phenyl-1,2-benzisoselenazol- 3(2H)-one or a salt thereof exhibits an excellent suppressive effect on retinal ganglion cell death in a pharmacological test using rats, and is therefore useful as a prophylactic or therapeutic agent for an eye disease accompanied by optic nerve disorder.

L'invention concerne une nouvelle application d'utilisation de la 2-phényl-1,2-benzisosélénazol-3(2H)-one ou d'un sel de celle-ci à des fins médicales. La 2-phényl-1,2-benzisosélénazol-3(2H)-one ou un sel de celle-ci possède un excellent effet inhibiteur sur la mort cellulaire des cellules des ganglions rétiniens dans un test pharmacologique sur des rats et est, par conséquent, utile comme agent prophylactique ou thérapeutique pour une maladie oculaire accompagnée d'un trouble du nerf optique.

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