C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/541.1
C07D 277/48 (2006.01)
Patent
CA 1266277
ABSTRACT OF THE DISCLOSURE Novel propionamidine derivatives of the formula: Image (I) wherein X is halogen, are disclosed, as well as a process for their preparation. The process involves reacting a 3-halopropionitrile of the formula: Image (III) wherein X is as defined above, with sulfamide of the formula: Image (II) in the presence of a hydrogen halide. The compounds of formula (I) are useful intermediates in the preparation of famotidine.
516618
Bod Peter
Csongor Eva Nee Agai
Dogsch Erik
Domany Gyorgy
Fekecs Eva
G. Ronald Bell & Associates
Richter Gedeon Vegyeszeti Gyar Rt
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