Propofol analogs, process for their preparation, and methods...

Details Propofol analogs, process for their preparation, and methods... Propofol analogs, process for their preparation, and methods...

C - Chemistry, Metallurgy

07

C

C07C 45/00 (2006.01) A61K 31/12 (2006.01)

Patent

CA 2551567

The invention provides para substituted dialkylphenol derivatives of propofol. The invention further provides pharmaceutical compositions comprising such analogs, methods for preparing such analogs, and methods of using such analogs to induce general anesthesia, sedation, and/or hypnotic or sleep effects in a patient.

La présente invention concerne des dérivés dialkylphénol para substitués du propofol. Cette invention concerne également des compositions pharmaceutiques comprenant de tels analogues, ainsi que des procédés permettant de préparer ces analogues. L'invention concerne également des méthodes permettant d'utiliser de tels analogues pour déclencher une anesthésie générale, une sédation, et/ou des effets hypnotiques ou soporifiques chez un patient.

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