Prostaglandin analogues

Details Prostaglandin analogues Prostaglandin analogues

C - Chemistry, Metallurgy

08

B

260/235.01

C08B 37/16 (2006.01) C07C 405/00 (2006.01) C07D 309/12 (2006.01) C07F 9/40 (2006.01) C08B 37/00 (2006.01)

Patent

CA 1091662

ABSTRACT Prostaglandin analogues of the general formula: Image (wherein A represents a grouping of the formula: Image , Image or Image , W represents ethylene or trans-vinylene, X represents ethylene or cis-vinylene, Y represents ethylene or trans-vinylene, R represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 12 carbon atoms, R represents a hydrogen atom or a methyl or ethyl group, R2 represents a straight- or branched-chain alkyl group containing from 2 to 8 carbon atoms, R3 represents a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 3 carbon atoms, and n represents 4 or 5) and cyclodextrin clathrates of such acids and esters and, when R represents a hydrogen atom, non-toxic salts thereof, are new compounds possessing pharmacological properties typical of the prostaglandins.

256941

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