Prostaglandin analogues as ep4 receptor agonists

Details Prostaglandin analogues as ep4 receptor agonists Prostaglandin analogues as ep4 receptor agonists

C - Chemistry, Metallurgy

07

D

C07D 207/26 (2006.01) A61K 31/4015 (2006.01) A61P 19/08 (2006.01) C07D 207/27 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 405/06 (2006.01) C07D 405/10 (2006.01)

Patent

CA 2451392

This invention relates to compounds according to Formula I or individual isomers, racemic or non-racemic mixtures of isomers, or pharmaceutically acceptable salts or solvates thereof, wherein A, B, R1 to R6 and Z are defined as in claim I. The invention further relates to pharmaceutical compositions comprising such compounds, the use of these compounds as therapeutic agents, and methods of preparation these compounds.

Cette invention concerne des composés de la formule (I) ou des isomères individuels, des mélanges racémiques ou non racémiques d'isomères, ou des sels pharmaceutiquement acceptables ou solvats desdits composés. Dans ladite formule, A, B, R1 à R6 et Z sont tels que définis dans la revendication I. L'invention concerne en outre des compositions pharmaceutiques comprenant ces composés, l'utilisation de ces composés comme agents thérapeutiques, et des méthodes de préparation de ces composés.

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