C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/205, 260/235
C07D 279/30 (2006.01) A61K 31/557 (2006.01) A61K 47/48 (2006.01) C07C 405/00 (2006.01)
Patent
CA 1246561
- 1 - Abstract The invention provides prostaglandin derivatives having cell membrane permeability characterized in that the carboxy group at the 1-position of the prostaglandin is combined with a cell membrane permeable substance selected from the group consisting of retinol, hydroxy- acetylretinol and phenothiazine through the mediation of an ester bond to the hydroxy group of the retinol or hydroxyacetylretinol group or an amide bond to the amino group of the phenothiazine. These compounds have much improved cell membrane permeability compared to the prostaglandins themselves.
494558
Hayaishi Osamu
Kimura Yoshiharu
Narumiya Shuh
Tsuboshima Masami
Kirby Eades Gale Baker
Research Development Corporation Of Japan
Tsuboshima Masami
LandOfFree
Prostaglandin derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Prostaglandin derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prostaglandin derivatives will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1227929