Prostaglandin e1 analogues

Details Prostaglandin e1 analogues Prostaglandin e1 analogues

C - Chemistry, Metallurgy

07

C

C07C 405/00 (2006.01) A61K 31/557 (2006.01)

Patent

CA 2147461

A prostaglandin E1 analogue represented by formula Image wherein R1 represents a hydrogen atom or a C1-C6 alkyl group; and X is an oxygen atom and R2 represents Image or Image , or X is a sulfur atom and R2 represents Image . The compound has a strong and prolonged inhibitory action for platelet aggregation and is useful for treatment of various thrombotic diseases including peripheral circu- latory disturbance.

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