Prostaglandin e2 (pge2) as an adjuvant in monoclonal...

Details Prostaglandin e2 (pge2) as an adjuvant in monoclonal... Prostaglandin e2 (pge2) as an adjuvant in monoclonal...

A - Human Necessities

61

K

A61K 31/5575 (2006.01) A61K 39/39 (2006.01)

Patent

CA 2664763

The present invention provides PGE2 as a novel adjuvant for enhancing the immune response in a host, as well as methods of using PGE2 to enhance B cell response and thereby increasing antibody titer against a given immnogen are aslo disclosed and antibodies produced by at least one method of the present invention.

La présente invention fournit une PGE2 en tant que nouvel adjuvant pour renforcer la réponse immune d'un hôte. Des procédés d'utilisation de PGE2 pour renforcer une réponse de cellule B et, par conséquent, pour augmenter le titre d'anticorps par rapport à un immunogène donné sont également décrits ainsi que les anticorps produits par au moins un procédé de la présente invention.

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