Prostaglandin ep4 receptor agonist and treatment method

A - Human Necessities – 61 – K

Patent

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Details

A61K 45/00 (2006.01) A61K 31/557 (2006.01) A61K 31/5585 (2006.01) A61P 13/12 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2332427

A prostaglandin EP4 receptor agonist containing as the active ingredient a prostaglandin I2 derivative. This compound binds strongly to prostaglandin EP4 receptor, which makes it useful as a pharmacological tool for clarifying physiological functions mediated by prostaglandin EP4 receptor or as a drug to be used in preventing/treating diseases in which prostaglandin EP4 receptor participates.

La présente invention concerne un agoniste du récepteur EP4 de la prostaglandine dont le principe actif est un dérivé de la prostaglandine I¿2?. Ce composé se lie fortement au récepteur EP4 de la prostaglandine, ce qui fait qu'il convient particulièrement, d'une part comme outil pharmacologique pour la mise en évidence de fonctions physologiques à médiation du récepteur EP4 de la prostaglandine, et d'autre part comme médicament de traitement ou de prévention d'affections dans lesquelles intervient le récepteur EP4 de la prostaglandine.

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