Prostaglandin f2.alpha. derivative-containing product

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/5575 (2006.01) A61J 1/05 (2006.01) A61K 9/08 (2006.01) A61K 47/34 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2592474

The invention provides a resin-made container which enables long-term stable preservation of aqueous liquid preparations containing prostaglandin F2.alpha. derivatives having fluorine atoms in the molecule. An aqueous liquid preparation containing a prostaglandin F2.alpha. derivative having a fluorine atom in the molecule is protected from lowering in the prostaglandin F2.alpha. derivative content by keeping the preparation in a container made of a propylene/ethylene copolymer having a propylene/ ethylene ratio of 94.0/6.0 to 99.5/0.5.

La présente invention concerne un récipient en résine qui permet une conservation longue durée stable de préparations liquides aqueuses contenant des dérivés de prostaglandine F2.alpha. portant des atomes de fluor. Il est notamment possible d'empêcher la diminution du taux de dérivé de prostaglandine F2.alpha. d~une préparation liquide aqueuse contenant un dérivé de prostaglandine F2.alpha. portant un atome de fluor en maintenant la préparation dans un récipient constitué d'un copolymère propylène/éthylène dont le rapport propylène/éthylène est compris entre 94,0/6,0 et 99,5/0,5.

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