C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 59/66 (2006.01) A61K 31/192 (2006.01) A61K 31/381 (2006.01) C07C 59/64 (2006.01) C07C 59/68 (2006.01) C07C 62/34 (2006.01) C07C 309/10 (2006.01) C07C 311/51 (2006.01) C07C 323/60 (2006.01) C07C 323/62 (2006.01) C07D 215/14 (2006.01) C07D 215/18 (2006.01) C07D 215/36 (2006.01) C07D 257/04 (2006.01) C07D 285/12 (2006.01) C07D 285/135 (2006.01) C07D 307/79 (2006.01) C07D 317/60 (2006.01) C07D 333/28 (2006.01) C07D 333/34 (2006.01)
Patent
CA 2346443
Compounds and methods for treating prostaglandin mediated diseases, and certain pharmaceutical compositions thereof are disclosed. The compounds are represented by formula (II): Ar1-W-Ar2-X-Q. The compounds of the invention are structurally different from NSAIDs and opiates, and are antagonists of the pain and inflammatory effects of E-type prostaglandins.
L'invention concerne des composés et des méthodes qui permettent de traiter les maladies ayant pour médiateurs les prostaglandines, ainsi que certaines compositions pharmaceutiques contenant lesdits composés. Ces composés, représentés par la formule (II) Ar?1¿-W-Ar?2¿-X-Q et structurellement différents des AINS et des opiacés, sont des antagonistes de la douleur et de l'inflammation provoquées par les prostaglandines de type E.
Belley Michel
Chauret Nathalie
Gallant Michel
Labelle Marc
Lachance Nicholas
Merck Frosst Canada Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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