Prostaglandin reductase

Details Prostaglandin reductase Prostaglandin reductase

C - Chemistry, Metallurgy

12

N

C12N 9/04 (2006.01) A61K 31/713 (2006.01) A61K 48/00 (2006.01) C07K 16/40 (2006.01)

Patent

CA 2507847

An isolated polypeptide containing the sequence of SEQ ID NO: 1 or a functional equivalent of SEQ ID NO: 1, in which the polypeptide reduces 15- keto prostaglandin but not leukotriene B4. Also disclosed is an antibody that binds specifically to the polypeptide and a double-stranded ribonucleic acid for inhibiting expression of the 15-keto prostaglandin-.DELTA.13-reductase.

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