Prostaglandin-type compounds and process for their preparation

C - Chemistry – Metallurgy – 07 – F

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260/235.03

C07F 9/54 (2006.01) C07C 405/00 (2006.01) C07D 303/40 (2006.01) C07D 307/935 (2006.01) C07D 309/12 (2006.01) C07F 7/08 (2006.01) C07F 7/18 (2006.01) C07F 9/40 (2006.01)

Patent

CA 1047491

ABSTRACT OF THE DISCLOSURE This invention is a group of 8-beta, 12-alpha-PGa (prostaglandin-type) analogs having variable chain length, or methyl or phenyl substitution in the hydroxy-substitiuted side-chain, and processes for making them, These compounds are useful for a variety of pharmacological purposes, including anti-ulcer, inhibition of platelet aggregation, increase of nasal patency, and labor inducement at term.

180595

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