Prostaglandins e and anti ulcer agents containing same

C - Chemistry – Metallurgy – 07 – C

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167/205, 260/235

C07C 405/00 (2006.01) A61K 31/557 (2006.01)

Patent

CA 1323364

557407 - 1 - Abstract: The novel 13, 14-dihydro-15-keto prostaglandins E of the invention have remarkable preventive effects against ulcers. Further, the novel 13,14-dihydro- 15-keto-prostaglandins E of the invention have the advantage that they have none of the side effects which prostaglandin E intrinsically has, or can remarkably reduce such effects of prostaglandin E. Therefore, the novel 13, 14-dihydro-15-keto prostaglandins E of the invention are effective for animal and human use in the treatment and prevention of ulcers, for example duodenal ulcers and gastric ulcers.

557407

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