Prostaglandins for use in medicine

Details Prostaglandins for use in medicine Prostaglandins for use in medicine

A - Human Necessities

61

K

167/205, 167/233

A61K 31/557 (2006.01) A61K 31/34 (2006.01) A61K 31/40 (2006.01)

Patent

CA 1327524

ABSTRACT Compounds for use in medicine The present invention is concerned with the use of a compound of formula (I) Image (I) wherein -W- is selected from Image (when Y is -N=) where a is 0 or 1, U is hydrogen or halogen and Z is -V(CH2)bCO2H where b is an integer of from 1 to 3 and V is oxygen or methylene; X is hydrogen, methyl, halogen, cyano, or -C=CH; Y is oxygen, methylene, -N=, or -N(Ar)- where Ar is an optionally substituted phenyl group; R is -(CH2)5R2 where R2 is hydrogen or methyl, or R is cyclohexyl, or R is -CH(CH3)CH2C=CCH3; R1 is hydrogen or methyl; and the dotted lines represent independently optional double bonds; and physiologically acceptable salts and acid derivatives thereof, in the manufacture of a medicament for the prophylaxis or treatment of pulmonary hypertension and in the manufacture of a diagnostic aid for identifying PPH (primary pulmonary hypertensive) patients having active pulmonary vasoconstriction. Medicaments and diagnostic aids obtained by the use of the invention which may be administered when primary or secondary pulmonary hypertension is indicated are also within the scope of the invention.

603021

Affiliated with

Also associated with

Rating

Prostaglandins for use in medicine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Prostaglandins for use in medicine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Prostaglandins for use in medicine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1196878